Why the Discovery of ‘LATE’ Dementia Is Important
When is Alzheimer’s disease not Alzheimer’s disease? It’s a riddle that finally has an answer.
Researchers recently pinpointed another form of cognitive decline with many of the same hallmarks as Alzheimer’s, but which actually involves different brain processes.
This newly discovered dementia may partly explain why some people haven’t been helped by current Alzheimer’s drugs or why some drugs being tested haven’t been as successful as scientists have hoped.
The disorder, dubbed “LATE,” stands for limbic-predominate age-related TDP-43 encephalopathy. Like Alzheimer’s, LATE affects short-term memory and causes cognitive impairment. It also shares some of the same disease traits as frontotemporal dementia.
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